2qux: Difference between revisions
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|PDB= 2qux |SIZE=350|CAPTION= <scene name='initialview01'>2qux</scene>, resolution 2.44Å | |PDB= 2qux |SIZE=350|CAPTION= <scene name='initialview01'>2qux</scene>, resolution 2.44Å | ||
|SITE= | |SITE= | ||
|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | |LIGAND= <scene name='pdbligand=A:ADENOSINE-5'-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5'-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5'-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=U:URIDINE-5'-MONOPHOSPHATE'>U</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= PP7 coat protein ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= | |GENE= PP7 coat protein ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12023 Pseudomonas phage PP7]) | ||
|DOMAIN= | |||
|RELATEDENTRY=[[1dwn|1DWN]], [[2qud|2QUD]] | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qux OCA], [http://www.ebi.ac.uk/pdbsum/2qux PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2qux RCSB]</span> | |||
}} | }} | ||
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==About this Structure== | ==About this Structure== | ||
2QUX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ | 2QUX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_phage_pp7 Pseudomonas phage pp7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QUX OCA]. | ||
==Reference== | ==Reference== | ||
Structural basis for the coevolution of a viral RNA-protein complex., Chao JA, Patskovsky Y, Almo SC, Singer RH, Nat Struct Mol Biol. 2008 Jan;15(1):103-5. Epub 2007 Dec 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18066080 18066080] | Structural basis for the coevolution of a viral RNA-protein complex., Chao JA, Patskovsky Y, Almo SC, Singer RH, Nat Struct Mol Biol. 2008 Jan;15(1):103-5. Epub 2007 Dec 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18066080 18066080] | ||
[[Category: | [[Category: Pseudomonas phage pp7]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Chao, J A.]] | [[Category: Chao, J A.]] | ||
[[Category: bacteriophage coat protein]] | [[Category: bacteriophage coat protein]] | ||
[[Category: capsid protein]] | [[Category: capsid protein]] | ||
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[[Category: structural protein/rna complex]] | [[Category: structural protein/rna complex]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:53:33 2008'' | ||
Revision as of 01:53, 31 March 2008
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| 2qux, resolution 2.44Å | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ligands: | A, C, G, GOL, U | ||||||||||||
| Gene: | PP7 coat protein (Pseudomonas phage PP7) | ||||||||||||
| Related: | 1DWN, 2QUD
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
PP7 coat protein dimer in complex with RNA hairpin
Overview
The cocrystal structure of the PP7 bacteriophage coat protein in complex with its translational operator identifies a distinct mode of sequence-specific RNA recognition when compared to the well-characterized MS2 coat protein-RNA complex. The structure reveals the molecular basis of the PP7 coat protein's ability to selectively bind its cognate RNA, and it demonstrates that the conserved beta-sheet surface is a flexible architecture that can evolve to recognize diverse RNA hairpins.
About this Structure
2QUX is a Single protein structure of sequence from Pseudomonas phage pp7. Full crystallographic information is available from OCA.
Reference
Structural basis for the coevolution of a viral RNA-protein complex., Chao JA, Patskovsky Y, Almo SC, Singer RH, Nat Struct Mol Biol. 2008 Jan;15(1):103-5. Epub 2007 Dec 9. PMID:18066080
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