6g31: Difference between revisions
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==Crystal structure of human geranylgeranyl diphosphate synthase mutant D188Y bound to zoledronate== | |||
<StructureSection load='6g31' size='340' side='right' caption='[[6g31]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6g31]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G31 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G31 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZOL:ZOLEDRONIC+ACID'>ZOL</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g31 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g31 OCA], [http://pdbe.org/6g31 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g31 RCSB], [http://www.ebi.ac.uk/pdbsum/6g31 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g31 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/GGPPS_HUMAN GGPPS_HUMAN]] Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Ben-Bassat, A]] | |||
[[Category: Giladi, M]] | |||
[[Category: Haitin, Y]] | |||
[[Category: Kapelushnik, N]] | |||
[[Category: Khananshvili, D]] | |||
[[Category: Lisnyansky, M]] | |||
[[Category: Loewenstein, A]] | |||
[[Category: Marom, M]] | |||
[[Category: Bisphosphonate]] | |||
[[Category: Geranylgeranyl diphosphate synthase]] | |||
[[Category: Ggpp]] | |||
[[Category: Mevalonate pathway]] | |||
[[Category: Prenyltransferase]] | |||
[[Category: Transferase]] | |||
