2rfn: Difference between revisions

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|PDB= 2rfn |SIZE=350|CAPTION= <scene name='initialview01'>2rfn</scene>, resolution 2.50&Aring;
|PDB= 2rfn |SIZE=350|CAPTION= <scene name='initialview01'>2rfn</scene>, resolution 2.50&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=AM7:2-benzyl-5-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-3-methylpyrimidin-4(3H)-one'>AM7</scene>
|LIGAND= <scene name='pdbligand=AM7:2-BENZYL-5-(3-FLUORO-4-{[6-METHOXY-7-(3-MORPHOLIN-4-YLPROPOXY)QUINOLIN-4-YL]OXY}PHENYL)-3-METHYLPYRIMIDIN-4(3H)-ONE'>AM7</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span>
|GENE= MET ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= MET ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[2rfs|2RFS]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rfn OCA], [http://www.ebi.ac.uk/pdbsum/2rfn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2rfn RCSB]</span>
}}
}}


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==Disease==
==Disease==
Known diseases associated with this structure: Autism, suseptibility to, 9 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Hepatocellular carcinoma, childhood type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Renal cell carcinoma, papillary, familial and sporadic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]]
Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Renal cell carcinoma, papillary, familial and sporadic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Autism, suseptibility to, 9 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]]


==About this Structure==
==About this Structure==
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[[Category: Yang, Y.]]
[[Category: Yang, Y.]]
[[Category: Zhang, Y.]]
[[Category: Zhang, Y.]]
[[Category: AM7]]
[[Category: atp-binding]]
[[Category: atp-binding]]
[[Category: c-met hgf receptor tyrosine kinse kinase domain]]
[[Category: c-met hgf receptor tyrosine kinse kinase domain]]
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[[Category: tyrosine-protein kinase]]
[[Category: tyrosine-protein kinase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:35:45 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:00:01 2008''