Main Page

ISSN 2310-6301 Because life is more than 2D, Proteopedia aids in understanding the 3D relationships between function & structure of biomacromolecules
Selected Pages	Art on Science	Journals	Education
Bacteria float with nano-balloons. ST Huber, D Terwiel, WH Evers, D Maresca, AJ Jakobi. Preprint 2022 doi: 10.1101/2022.05.08.489936 Many kinds of bacteria and archaea control their buoyancy to move to optimal positions in liquid environments. They do this by making nano-compartments called "gas vesicles", long "pipes" with closed ends filled with gases. In 2022, gas vesicle structure was solved, revealing self-assembling thin-walled cylinders of remarkable strength with gas-permeable pores and water-repelling (hydrophobic) interiors. Building on this structural knowledge, gas vesicles are being engineered to serve as biosensors that report via ultrasound. >>> Visit I3DC Interactive Visualizations >>>	Molecular Sculpture by Eric Martz A historical review on sculptures and physical models of macromolecules. >>> Visit this page >>>	Structural flexibility of the periplasmic protein, FlgA, regulates flagellar P-ring assembly in Salmonella enterica. H Matsunami, YH Yoon, VA Meshcheryakov, K Namba, FA Samatey. Scientific Reports 2016 doi: 10.1038/srep27399 A periplasmic flagellar chaperone protein, FlgA, is required for P-ring assembly in bacterial flagella of taxa such as Salmonella enterica or Escherichia coli. Here we present the open and closed crystal structures of FlgA from Salmonella enterica serovar Typhimurium, grown under different crystallization conditions. An intramolecular disulfide cross-linked form of FlgA caused a dominant negative effect on motility of the wild-type strain. >>> Visit this I3DC complement >>>	Touch-Sensitive Channel Touching stretches cell membranes, opening mechanosensitive ion channels, leading to sensation by the nervous system. Pictured is the transmembrane region of a similar channel in bacteria. When closed, the narrow opening is lined by hydrophobic amino acid sidechains, making it non-conductive to ions. >>> See more animations and explanation >>>
How to add content to Proteopedia Video Guides Who knows ...	List of Art on Science pages in Proteopedia	What is an Interactive 3D Complement (I3DC)? List of I3DCs How to get an I3DC for your paper	Teaching Strategies Using Proteopedia Examples of Pages for Teaching How to add content to Proteopedia
About Table of Contents Structure Index Help

Proteopedia Page Contributors and Editors (what is this?)

Jaime Prilusky, Joel L. Sussman, Angel Herraez