5z4m: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5z4m is ~~ON HOLD until Jan 12 2020~~

==Structure of TailorD343A with bound UTP and Mg==

~~Authors~~: ~~Cheng~~, L., Li, F., ~~Jiang~~, Y.~~, Yu, H~~.~~, Xie, C~~., ~~Shi, Y~~.~~, Gong, Q~~.

== Structural highlights ==

<table><tr><td colspan='2'>[[5z4m]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z4M OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Z4M FirstGlance].

~~Description~~: ~~Structure~~ of ~~TailorD343A with bound UTP~~ and Mg

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/RNA_uridylyltransferase RNA uridylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.52 2.7.7.52] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5z4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z4m OCA], [http://pdbe.org/5z4m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z4m RCSB], [http://www.ebi.ac.uk/pdbsum/5z4m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z4m ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/TUTT_DROME TUTT_DROME]] Uridylyltransferase which mediates terminal uridylation of miRNAs, leading to their degradation. Has high specificity for splicing-derived miRNAs (mirtrons) and other miRNA substrates containing a 3'-G terminal nucleotide. Appears to be a major suppressor of mirtron biogenesis.<ref>PMID:26145174</ref> <ref>PMID:26145176</ref>

== References ==

__TOC__

</StructureSection>

[[Category: RNA uridylyltransferase]]

[[Category: Cheng, L]]

~~[[Category: Yu, H]]~~

[[Category: Gong, Q]]

[[Category: Jiang, Y]]

[[Category: Li, F]]

[[Category: Shi, Y]]

~~[[Category: Jiang, Y]]~~

[[Category: Xie, C]]

[[Category: Li, F]]

[[Category: Yu, H]]

[[Category: Terminal uridylyltransferase]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5z4m is ON HOLD  until Jan 12 2020
+==Structure of TailorD343A with bound UTP and Mg==
+<StructureSection load='5z4m' size='340' side='right' caption='[[5z4m]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
-Authors: Cheng, L., Li, F., Jiang, Y., Yu, H., Xie, C., Shi, Y., Gong, Q.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5z4m]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z4M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Z4M FirstGlance]. <br>
-Description: Structure of TailorD343A with bound UTP and Mg
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_uridylyltransferase RNA uridylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.52 2.7.7.52] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5z4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z4m OCA], [http://pdbe.org/5z4m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z4m RCSB], [http://www.ebi.ac.uk/pdbsum/5z4m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z4m ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/TUTT_DROME TUTT_DROME]] Uridylyltransferase which mediates terminal uridylation of miRNAs, leading to their degradation. Has high specificity for splicing-derived miRNAs (mirtrons) and other miRNA substrates containing a 3'-G terminal nucleotide. Appears to be a major suppressor of mirtron biogenesis.<ref>PMID:26145174</ref> <ref>PMID:26145176</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: RNA uridylyltransferase]]
 [[Category: Cheng, L]]
-[[Category: Yu, H]]
 [[Category: Gong, Q]]
+[[Category: Jiang, Y]]
+[[Category: Li, F]]
 [[Category: Shi, Y]]
-[[Category: Jiang, Y]]
 [[Category: Xie, C]]
-[[Category: Li, F]]
+[[Category: Yu, H]]
+[[Category: Terminal uridylyltransferase]]
+[[Category: Transferase]]