6gd2: Difference between revisions

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'''Unreleased structure'''


The entry 6gd2 is ON HOLD until Paper Publication
==Structure of HuR RRM3 in complex with RNA==
 
<StructureSection load='6gd2' size='340' side='right' caption='[[6gd2]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6gd2]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GD2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GD2 FirstGlance]. <br>
Description:  
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gd2 OCA], [http://pdbe.org/6gd2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gd2 RCSB], [http://www.ebi.ac.uk/pdbsum/6gd2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gd2 ProSAT]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
== Function ==
[[http://www.uniprot.org/uniprot/ELAV1_HUMAN ELAV1_HUMAN]] Involved in 3'-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro.<ref>PMID:19029303</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Pabis, M]]
[[Category: Sattler, M]]
[[Category: Rna binding protein]]
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