Sialidase: Difference between revisions
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<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | |||
== Function == | |||
'''Salisidase''' is a neuraminidase which cleaves terminal sialic acid from a variety of natural substances <ref>PMID:12374200</ref>. | |||
== Disease == | |||
== Relevance == | |||
== Structural highlights == | |||
</StructureSection> | |||
==3D structures of salisidase== | |||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | |||
{{#tree:id=OrganizedByTopic|openlevels=0| | |||
*Salisidase | |||
**[[1eur]] - MvNANA residues 43-407 – ''Micromonospora viridifaciens''<br /> | |||
**[[1euu]] - MvNANA residues 47-647<br /> | |||
**[[1wcq]], [[1w8n]], [[1w8o]], [[2hu0]], [[2hu4]] – MvNANA residues 47-647 (mutant) <br /> | |||
**[[5mqr]], [[5mqs]], [[4bbw]], [[5muk]], [[5mul]] - BtSal - ''Bacterioides thetaiotaomicron'' <br /> | |||
** [[1mz5]], [[1n1s]] - TrSal - ''Trypanosoma rangeli''<br /> | |||
** [[1wcs]] - TrSal (mutant) <br /> | |||
**[[3sil]] – StSal (mutant) – ''Salmonella typhimurium''<br /> | |||
**[[1snt]], [[1so7]] – hSal2 - human<br /> | |||
**[[2f24]], [[2f26]], [[2f28]] – hSal2 (mutant) <br /> | |||
**[[2w20]] – SpSal A catalytic domain - ''Streptococcus pneumoniae''<br /> | |||
**[[4zxk]] – SpSal A CBD <br /> | |||
**[[2vw0]], [[2vw2]], [[4xik]], [[2ya4]], [[2w20]], [[2vvz]], [[3h71]] - SpSal B<br /> | |||
** [[4xmi]], [[4xio]], [[4xj8]], [[4xma]], [[4xjz]], [[4xik]] - SpSal B (mutant) <br /> | |||
**[[4yw4]] – SpSal C <br /> | |||
**[[2xzi]], [[2xzj]], [[2xzk]], [[2xcy]] – AfSal – ''Aspergillus fumigatus''<br /> | |||
** [[4m4n]], [[4m4u]] - AfSal (mutant) <br /> | |||
**[[1sll]] – Sal L - leech<br /> | |||
**[[2vk5]], [[5tsp]] - CpSal I – ''Clostridium perfringens''<br /> | |||
*Salisidase complexes | |||
**[[2w68]] – VcSal CBD + sialic acid – ''Vibrio cholerae''<br /> | |||
**[[1kit]]– VcSal + sialic acid <br /> | |||
**[[1w0p]] – VcSal + sialic acid derivative<br /> | |||
**[[6eks]], [[6eku]] – VcSal + drug<br /> | |||
**[[3h72]], [[2ya5]] – SpSal A + sialic acid <br /> | |||
**[[4c1w]], [[4c1x]] – SpSal A CBD + sialic acid derivative<br /> | |||
**[[2ya7]], [[2ya8]], [[5kky]], [[5f9t]], [[2ya6]], [[2jkb]] - SpSal A catalytic domain + drug<br /> | |||
**[[2vvz]], [[3h73]] – SpSal A + neuraminic acid derivative <br /> | |||
**[[2vw1]] – SpSal B + neuraminic acid derivative <br /> | |||
**[[4xyx]] – SpSal B + drug<br /> | |||
**[[4xog]], [[4xjw]], [[4xj9]], [[4xil]], [[4xe9]] – SpSal B (mutant) + drug<br /> | |||
**[[4foq]], [[4fov]], [[4fow]], [[4foy]], [[4fp2]], [[4fp3]], [[4fpc]], [[4fpe]], [[4fpf]], [[4fpg]], [[4fph]], [[4fpj]], [[4fpk]], [[4fpl]], [[4fpo]], [[4fpy]], [[4fq4]] – SpSal B + inhibitor<br /> | |||
**[[4xju]], [[4xja]], [[4xhx]], [[4xhb]] – SpSal B (mutant) + inhibitor<br /> | |||
**[[2jkb]] – SpSal B + sialic acid derivative<br /> | |||
**[[4yz3]], [[4yw5]] – SpSal C + drug<br /> | |||
**[[4yw2]] – SpSal C + sialic acid <br /> | |||
**[[4yz4]], [[4yz2]] – SpSal C + neuraminic acid derivative <br /> | |||
**[[4yw1]], [[4yw3]] – SpSal C + sialic acid + neuraminic acid derivative<br /> | |||
**[[1w0o]] – VcSal + sialic acid + neuraminic acid derivative<br /> | |||
**[[2vk6]], [[2vk7]] – CpSal I + neuraminic acid derivative <br /> | |||
**[[2bf6]] – CpSal I residues 243-691 + sialic acid <br /> | |||
**[[5fra]], [[5fre]] – CpSal I CBD + sialic acid <br /> | |||
**[[2v73]]– CpSal J CBD + sialic acid <br /> | |||
**[[2v72]]– CpSal J CBD + galactose <br /> | |||
**[[1n1v]] – TrSal + neuraminic acid derivative <br /> | |||
**[[1mz6]], [[1n1t]], [[2ags]] – TrSal + inhibitor <br /> | |||
**[[1n1y]]– TrSal + sialic acid <br /> | |||
**[[2a75]], [[2fhr]] – TrSal + sialic acid derivative<br /> | |||
**[[1dim]], [[1dil]], [[2sil]], [[2sim]] – StSal + inhibitor - ''Salmonella typhimurium'' <br /> | |||
**[[1eus]] - MvSal residues 43-407 + neuraminic acid derivative<br /> | |||
**[[1eut]] - MvSal residues 47-647 + galactose<br /> | |||
**[[2bzd]] - MvSal residues 47-647 (mutant) + galactose<br /> | |||
**[[1w80]] - MvSal residues 47-647 (mutant) + lactose<br /> | |||
**[[1wcq]], [[1w8n]] – MvSal (mutant) + neuraminic acid derivative<br /> | |||
**[[2ber]] – MvSal (mutant) + sialic acid derivative<br /> | |||
**[[4m4v]] – AfSal (mutant) + neuraminic acid derivative<br /> | |||
**[[1vcu]], [[2f0z]], [[2f10]], [[2f11]], [[2f12]], [[2f13]] - hSal2 + inhibitor<br /> | |||
**[[2f25]], [[2f27]], [[2f29]], [[4nc5]], [[4ncs]] - hSal2 (mutant) + inhibitor<br /> | |||
**[[5mul]] – BtSal + glucuronic acid<br /> | |||
*'''Trans-sialidase''' | |||
}} | |||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | |||