3cjo: Difference between revisions
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==Crystal structure of KSP in complex with inhibitor 30== | ==Crystal structure of KSP in complex with inhibitor 30== | ||
<StructureSection load='3cjo' size='340' side='right' caption='[[3cjo]], [[Resolution|resolution]] 2.28Å' scene=''> | <StructureSection load='3cjo' size='340' side='right' caption='[[3cjo]], [[Resolution|resolution]] 2.28Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=K30:(2S)-4-(2,5-DIFLUOROPHENYL)-N-[(3R,4S)-3-FLUORO-1-METHYLPIPERIDIN-4-YL]-2-(HYDROXYMETHYL)-N-METHYL-2-PHENYL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE'>K30</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=K30:(2S)-4-(2,5-DIFLUOROPHENYL)-N-[(3R,4S)-3-FLUORO-1-METHYLPIPERIDIN-4-YL]-2-(HYDROXYMETHYL)-N-METHYL-2-PHENYL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE'>K30</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KIF11, EG5, KNSL1, TRIP5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KIF11, EG5, KNSL1, TRIP5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cjo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cjo OCA], [http://pdbe.org/3cjo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cjo RCSB], [http://www.ebi.ac.uk/pdbsum/3cjo PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cjo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cjo OCA], [http://pdbe.org/3cjo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cjo RCSB], [http://www.ebi.ac.uk/pdbsum/3cjo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3cjo ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cj/3cjo_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cj/3cjo_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Cell division]] | [[Category: Cell division]] | ||
[[Category: Coiled coil]] | |||
[[Category: Ksp]] | [[Category: Ksp]] | ||
[[Category: Ksp-inhibitor complex]] | [[Category: Ksp-inhibitor complex]] | ||
