5yqb: Difference between revisions

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'''Unreleased structure'''


The entry 5yqb is ON HOLD  until Paper Publication
==Crystal structure of E.coli aminopeptidase N in complex with Puromycin==
 
<StructureSection load='5yqb' size='340' side='right' caption='[[5yqb]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
Authors: Marapaka, A.K., Ganji, R.J., Reddi, R., Addlagatta, A.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5yqb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YQB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YQB FirstGlance]. <br>
Description: Crystal structure of E.coli aminopeptidase N in complex with Puromycin
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0A1:O-METHYL-L-TYROSINE'>0A1</scene>, <scene name='pdbligand=GMC:(2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL'>GMC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Membrane_alanyl_aminopeptidase Membrane alanyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.2 3.4.11.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yqb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yqb OCA], [http://pdbe.org/5yqb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yqb RCSB], [http://www.ebi.ac.uk/pdbsum/5yqb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yqb ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/AMPN_ECOLI AMPN_ECOLI]] Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation.
__TOC__
</StructureSection>
[[Category: Membrane alanyl aminopeptidase]]
[[Category: Addlagatta, A]]
[[Category: Addlagatta, A]]
[[Category: Ganji, R.J]]
[[Category: Ganji, R J]]
[[Category: Marapaka, A.K]]
[[Category: Marapaka, A K]]
[[Category: Reddi, R]]
[[Category: Reddi, R]]
[[Category: Hydrolase]]
[[Category: M1 class aminopeptidase]]
[[Category: Puromycin]]