6i8b: Difference between revisions
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==Crystal structure of Spindlin1 in complex with the inhibitor VinSpinIn== | |||
<StructureSection load='6i8b' size='340' side='right' caption='[[6i8b]], [[Resolution|resolution]] 1.76Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6i8b]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I8B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I8B FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=H7T:2-[4-[2-[[2-[3-[2-azanyl-5-(cyclopropylmethoxy)-3,3-dimethyl-indol-6-yl]oxypropyl]-1,3-dihydroisoindol-5-yl]oxy]ethyl]-1,2,3-triazol-1-yl]-1-[4-(2-pyrrolidin-1-ylethyl)piperidin-1-yl]ethanone'>H7T</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i8b OCA], [http://pdbe.org/6i8b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i8b RCSB], [http://www.ebi.ac.uk/pdbsum/6i8b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i8b ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/SPIN1_HUMAN SPIN1_HUMAN]] May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Arrowsmith, C H]] | |||
[[Category: Bountra, C]] | |||
[[Category: Brennan, P E]] | |||
[[Category: Edwards, A]] | |||
[[Category: Fagan, V]] | [[Category: Fagan, V]] | ||
[[Category: Johansson, C]] | [[Category: Johansson, C]] | ||
[[Category: Krojer, T]] | [[Category: Krojer, T]] | ||
[[Category: | [[Category: Oppermann, U C.T]] | ||
[[Category: Sorrell, F | [[Category: Sorrell, F J]] | ||
[[Category: Cell cycle]] | |||
[[Category: Epigenetic]] | |||
[[Category: Methyl-arginine]] | |||
[[Category: Methyl-lysine]] | |||
[[Category: Tudor domain]] | |||
Revision as of 06:48, 5 December 2018
Crystal structure of Spindlin1 in complex with the inhibitor VinSpinIn
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