Sandbox Reserved 1475: Difference between revisions
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[[Image:Figure 3.png|thumb|upright=1.5| [[Figure 3]] Section (a) is the dimer of RalDH2 with the green spheres representing the amino and carboy termini of the substrate access channel loop. Section (b) shows the same orientation as section (a) with both dimers present and then the two dimers spun 90 degrees on the X-axis.<ref name="Lamb AL, Newcomber ME" /> ]] | [[Image:Figure 3.png|thumb|upright=1.5| [[Figure 3]] Section (a) is the dimer of RalDH2 with the green spheres representing the amino and carboy termini of the substrate access channel loop. Section (b) shows the same orientation as section (a) with both dimers present and then the two dimers spun 90 degrees on the X-axis.<ref name="Lamb AL, Newcomber ME" /> ]] | ||
<Structure load='1BI9' size='350' frame='true' align='right' caption='[[Figure 4]] Highlighted Cys-302 in yellow, Glu-268 in green, and Asn-187 in red (PDB entry [[1bi9]])' <scene name='80/800654/Catalytic_site/1' | <Structure load='1BI9' size='350' frame='true' align='right' caption='[[Figure 4]] Highlighted Cys-302 in yellow, Glu-268 in green, and Asn-187 in red (PDB entry [[1bi9]])' <scene name='80/800654/Catalytic_site/1'/> | ||
The structure was based on the mitochondrial aldehyde dehydrogenase type two. RalDH2 in a monomer made up of 3 domains: a nucleotide-binding domain (1-136, 161-270), a catalytic domain (271-484), and a tetramerization domain (137-160, 485-484) as shown in [[Figure 1]].<ref name="Lamb AL, Newcomber ME" /> | The structure was based on the mitochondrial aldehyde dehydrogenase type two. RalDH2 in a monomer made up of 3 domains: a nucleotide-binding domain (1-136, 161-270), a catalytic domain (271-484), and a tetramerization domain (137-160, 485-484) as shown in [[Figure 1]].<ref name="Lamb AL, Newcomber ME" /> | ||
