6dhb: Difference between revisions

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'''Unreleased structure'''


The entry 6dhb is ON HOLD  until Paper Publication
==Crystal structure of the human TIM-3 with bound Calcium==
 
<StructureSection load='6dhb' size='340' side='right' caption='[[6dhb]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
Authors: Gandhi, A.K., Kim, W.M., Huang, Y.H., Bonsor, D., Sundberg, E., Sun, Z.-Y., Petsko, G.A., Kuchroo, V., Blumberg, R.S.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6dhb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DHB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DHB FirstGlance]. <br>
Description: Crystal structure of the human TIM-3 with bound Calcium
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dhb OCA], [http://pdbe.org/6dhb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dhb RCSB], [http://www.ebi.ac.uk/pdbsum/6dhb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dhb ProSAT]</span></td></tr>
[[Category: Sundberg, E]]
</table>
[[Category: Petsko, G.A]]
== Function ==
[[Category: Kim, W.M]]
[[http://www.uniprot.org/uniprot/HAVR2_HUMAN HAVR2_HUMAN]] Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.<ref>PMID:14556005</ref> <ref>PMID:16286920</ref> 
[[Category: Blumberg, R.S]]
== References ==
[[Category: Gandhi, A.K]]
<references/>
[[Category: Huang, Y.H]]
__TOC__
[[Category: Sun, Z.-Y]]
</StructureSection>
[[Category: Blumberg, R S]]
[[Category: Bonsor, D]]
[[Category: Bonsor, D]]
[[Category: Gandhi, A K]]
[[Category: Huang, Y H]]
[[Category: Kim, W M]]
[[Category: Kuchroo, V]]
[[Category: Kuchroo, V]]
[[Category: Petsko, G A]]
[[Category: Sun, Z Y]]
[[Category: Sundberg, E]]
[[Category: Immune system]]
[[Category: T cell immunoglobulin mucin-3 immunological tolerance]]