6dtv: Difference between revisions
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==Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y395F mutant== | |||
<StructureSection load='6dtv' size='340' side='right' caption='[[6dtv]], [[Resolution|resolution]] 1.12Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6dtv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DTV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DTV FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> | |||
[[ | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6di2|6di2]], [[6di6|6di6]], [[6dtz|6dtz]], [[6du0|6du0]]</td></tr> | ||
[[Category: Chazin, W | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dtv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dtv OCA], [http://pdbe.org/6dtv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dtv RCSB], [http://www.ebi.ac.uk/pdbsum/6dtv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dtv ProSAT]</span></td></tr> | ||
[[Category: Salay, L | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/PRI2_YEAST PRI2_YEAST]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase. Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Chazin, W J]] | |||
[[Category: Salay, L E]] | |||
[[Category: Dna primase]] | |||
[[Category: Iron-sulfur cluster]] | |||
[[Category: P58]] | |||
[[Category: Regulatory subunit]] | |||
[[Category: Replication]] | |||
Revision as of 06:44, 12 December 2018
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y395F mutant
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