6h6y: Difference between revisions
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==GI.1 human norovirus protruding domain in complex with Nano-7== | |||
<StructureSection load='6h6y' size='340' side='right' caption='[[6h6y]], [[Resolution|resolution]] 1.58Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6h6y]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H6Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H6Y FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6h6z|6h6z]], [[6h70|6h70]], [[6h71|6h71]], [[6h72|6h72]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h6y OCA], [http://pdbe.org/6h6y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h6y RCSB], [http://www.ebi.ac.uk/pdbsum/6h6y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h6y ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CAPSD_NVN68 CAPSD_NVN68]] Capsid protein self assembles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins. A smaller form of capsid with a diameter of 23 nm might be capsid proteins assembled as icosahedron with T=1 symmetry. The capsid encapsulate the genomic RNA and VP2 proteins. Attaches virion to target cells by binding histo-blood group antigens present on gastroduodenal epithelial cells.<ref>PMID:16840313</ref> Soluble capsid protein may play a role in viral immunoevasion.<ref>PMID:16840313</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Hansman, G S]] | |||
[[Category: Kilic, T]] | |||
[[Category: Ruoff, K]] | [[Category: Ruoff, K]] | ||
[[Category: | [[Category: Gi 1]] | ||
[[Category: | [[Category: Nano-7]] | ||
[[Category: Norovirus]] | |||
[[Category: P domain]] | |||
[[Category: Viral protein]] | |||
Revision as of 08:29, 19 December 2018
GI.1 human norovirus protruding domain in complex with Nano-7
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