6h72: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 6h72 is ON HOLD~~

==GI.1 human norovirus protruding domain in complex with Nano-94 and 2-fucosyllactose (2FL)==

~~Authors: Kilic, T., Hansman, G.S.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[6h72]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H72 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H72 FirstGlance].

~~Description:~~ GI.1 human norovirus protruding domain in complex with Nano-94 and 2-fucosyllactose (2FL)

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

[[Category: Hansman, G.S]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h72 OCA], [http://pdbe.org/6h72 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h72 RCSB], [http://www.ebi.ac.uk/pdbsum/6h72 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h72 ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/CAPSD_NVN68 CAPSD_NVN68]] Capsid protein self assembles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins. A smaller form of capsid with a diameter of 23 nm might be capsid proteins assembled as icosahedron with T=1 symmetry. The capsid encapsulate the genomic RNA and VP2 proteins. Attaches virion to target cells by binding histo-blood group antigens present on gastroduodenal epithelial cells.<ref>PMID:16840313</ref> Soluble capsid protein may play a role in viral immunoevasion.<ref>PMID:16840313</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Hansman, G S]]

[[Category: Kilic, T]]

[[Category: 2-fucosyllactose]]

[[Category: Gi 1]]

[[Category: Nano-94]]

[[Category: Norovirus]]

[[Category: P domain]]

[[Category: Viral protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6h72 is ON HOLD
+==GI.1 human norovirus protruding domain in complex with Nano-94 and 2-fucosyllactose (2FL)==
+<StructureSection load='6h72' size='340' side='right' caption='[[6h72]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-Authors: Kilic, T., Hansman, G.S.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6h72]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H72 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H72 FirstGlance]. <br>
-Description: GI.1 human norovirus protruding domain in complex with Nano-94 and 2-fucosyllactose (2FL)
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6h6y|6h6y]], [[6h6z|6h6z]], [[6h70|6h70]], [[6h71|6h71]]</td></tr>
-[[Category: Hansman, G.S]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h72 OCA], [http://pdbe.org/6h72 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h72 RCSB], [http://www.ebi.ac.uk/pdbsum/6h72 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h72 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/CAPSD_NVN68 CAPSD_NVN68]] Capsid protein self assembles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins. A smaller form of capsid with a diameter of 23 nm might be capsid proteins assembled as icosahedron with T=1 symmetry. The capsid encapsulate the genomic RNA and VP2 proteins. Attaches virion to target cells by binding histo-blood group antigens present on gastroduodenal epithelial cells.<ref>PMID:16840313</ref>   Soluble capsid protein may play a role in viral immunoevasion.<ref>PMID:16840313</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Hansman, G S]]
 [[Category: Kilic, T]]
+[[Category: 2-fucosyllactose]]
+[[Category: Gi 1]]
+[[Category: Nano-94]]
+[[Category: Norovirus]]
+[[Category: P domain]]
+[[Category: Viral protein]]