Base stacking: Difference between revisions

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Karsten Theis (talk | contribs)
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# '''DNA double helix''': In <scene name='80/804504/Dna/3'>double-stranded DNA</scene>, bases from two strands pair up to form base pairs, which are stacked along the helix axis of the double strand. Zooming in to a detailed view of a <scene name='80/804504/Dna/5'>G:C base pair</scene>, the extent of the stacking contacts are determined by the sequence. G:C base pairs contribute more to the thermal stability of DNA than A:T base pairs because they stack better.
# '''DNA double helix''': In <scene name='80/804504/Dna/3'>double-stranded DNA</scene>, bases from two strands pair up to form base pairs, which are stacked along the helix axis of the double strand. Zooming in to a detailed view of a <scene name='80/804504/Dna/5'>G:C base pair</scene>, the extent of the stacking contacts are determined by the sequence. G:C base pairs contribute more to the thermal stability of DNA than A:T base pairs because they stack better.
# '''RNA kissing loops''': <scene name='80/804504/Kissing_loop/2'>Loops on two separate RNA pieces</scene> are held together by stacking interactions (between base pairs) and hydrogen bonds (within base pairs).
# '''RNA kissing loops''': Loops on two separate RNA pieces are held together by <scene name='80/804504/Kissing_loop/2'>stacking interactions</scene> (between base pairs) and<scene name='80/804504/Kissing_loop/4'> hydrogen bonds</scene> (within base pairs).
# '''RNA single strand bound to a protein''': In this <scene name='80/804504/Intercalation/2'>complex of RNA bound to a protein</scene>, some of the stacking interactions are disrupted by amino acid side chains (such as arginine, histidine and tyrosine) intercalating between adjacent bases. <jmol>
# '''RNA single strand bound to a protein''': In this <scene name='80/804504/Intercalation/2'>complex of RNA bound to a protein</scene>, some of the stacking interactions are disrupted by amino acid side chains (such as arginine, histidine and tyrosine) intercalating between adjacent bases. <jmol>
   <jmolRadioGroup>
   <jmolRadioGroup>
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