6isb: Difference between revisions
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==crystal structure of human CD226== | |||
<StructureSection load='6isb' size='340' side='right' caption='[[6isb]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6isb]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ISB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ISB FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6isb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6isb OCA], [http://pdbe.org/6isb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6isb RCSB], [http://www.ebi.ac.uk/pdbsum/6isb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6isb ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CD226_HUMAN CD226_HUMAN]] Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell (PubMed:8673704). Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding (PubMed:26755705).<ref>PMID:26755705</ref> <ref>PMID:8673704</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Gao, G F]] | |||
[[Category: Li, Y]] | |||
[[Category: Qi, J]] | |||
[[Category: Tan, S]] | |||
[[Category: Wang, H]] | |||
[[Category: Zhang, S]] | |||
[[Category: Cd226]] | |||
[[Category: Dnam-1]] | |||
[[Category: Immune system]] | |||
