Sandbox Reserved 1488: Difference between revisions
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==Function == | ==Function == | ||
The bacterial cell wall is essential for cell survival. It is composed of layers of peptidoglycan modified with proteins and polymers. In bacteria, this peptidoglycan layer is formed by the coordinated action of multiple proteins, including penicillin-binding proteins (PBPs). PBPs are transpeptidases, carboxypeptidases and endopeptidases that synthesize new and remodel existing peptidoglycan. | |||
PBPs are classified by their enzymatic activity: | |||
(1) class A, bifunctional PBPs with both glycosyltransferase and transpeptidase activities; | |||
(2) class B, transpeptidases; and | |||
(3) class C, carboxy-peptidases and endopeptidases. | |||
== Disease == | == Disease == | ||
