Sandbox Reserved 1501: Difference between revisions

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== Function ==
== Function ==
== Disease ==


== Relevance ==
== Relevance ==


By being a component of the mitochondrial inter membrane space cytochrome b2 has a relevance for the lactate metabolic process.
While the function of cytochrome b2 is to couple L-lactate dehydrogenation to cytochrome c reduction; the mutant ARG289LYS is changing the kinetics of the reactions. It is rising the K<sub>i</sub> of several components in comparison to the wild-type, while k<sub>cat</sub> and K<sub>M</sub> are also changed by a factor of 10. It changes also the induction by L-lactate.
R289K-b(2)
eing a component of the mitochondrial inter membrane space


== Structural highlights ==
== Structural highlights ==