Sandbox Reserved 1493: Difference between revisions
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The '''headpiece''' (2VDL) of integrin αIIbβ3 enables cation-facilitated ligand binding with multiple ligands (most known being [[fibrinogen]], [[fibronectin]], von Willebrand factors, [[thrombospondin]] and vitronectin). Binding affinity is dynamic and depends on the conformational status of the receptor. | The '''headpiece''' (2VDL) of integrin αIIbβ3 enables cation-facilitated ligand binding with multiple ligands (most known being [[fibrinogen]], [[fibronectin]], von Willebrand factors, [[thrombospondin]] and vitronectin). Binding affinity is dynamic and depends on the conformational status of the receptor. | ||
''Jmol displays residues 32-483 of αIIb and residues 27-487 of β3. In order to have a global view | ''Jmol displays residues 32-483 of αIIb and residues 27-487 of β3. In order to have a global view of the integrin, refer to pictures.'' | ||
<StructureSection load='2vdl' size='340' side='right' caption='2VDL Headpiece of integrin αIIbβ3' scene=''> | <StructureSection load='2vdl' size='340' side='right' caption='2VDL Headpiece of integrin αIIbβ3' scene=''> | ||
