6dg5: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6dg5 ~~is ON HOLD until Paper Publication~~

==Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic complex with IL-2Rb and IL-2Rg==

~~Authors~~: ~~Jude, K~~.M., ~~Silva~~, D.-A., Yu, S., ~~Baker~~, D., ~~Garcia, K~~.C.

== Structural highlights ==

<table><tr><td colspan='2'>[[6dg5]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DG5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DG5 FirstGlance]. <br>

~~Description~~: ~~Structure~~ of ~~a de novo designed Interleukin-2/Interleukin-15 mimetic complex with IL-2Rb and IL-2Rg~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dg5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dg5 OCA], [http://pdbe.org/6dg5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dg5 RCSB], [http://www.ebi.ac.uk/pdbsum/6dg5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dg5 ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/IL2RG_MOUSE IL2RG_MOUSE]] Common subunit for the receptors for a variety of interleukins. [[http://www.uniprot.org/uniprot/IL2RB_MOUSE IL2RB_MOUSE]] Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

__TOC__

</StructureSection>

[[Category: Baker, D]]

[[Category: ~~Silva~~, ~~D.-A~~]]

[[Category: Garcia, K C]]

[[Category: Jude, K.M]]

[[Category: Jude, K M]]

[[Category: ~~Garcia~~, ~~K.C~~]]

[[Category: Silva, D A]]

[[Category: Yu, S]]

[[Category: Biosynthetic protein]]

[[Category: Biosynthetic protein-protein binding complex]]

[[Category: Cytokine mimetic]]

[[Category: Cytokine receptor complex]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6dg5 is ON HOLD  until Paper Publication
+==Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic complex with IL-2Rb and IL-2Rg==
+<StructureSection load='6dg5' size='340' side='right' caption='[[6dg5]], [[Resolution|resolution]] 2.52&Aring;' scene=''>
-Authors: Jude, K.M., Silva, D.-A., Yu, S., Baker, D., Garcia, K.C.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6dg5]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DG5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DG5 FirstGlance]. <br>
-Description: Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic complex with IL-2Rb and IL-2Rg
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dg5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dg5 OCA], [http://pdbe.org/6dg5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dg5 RCSB], [http://www.ebi.ac.uk/pdbsum/6dg5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dg5 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/IL2RG_MOUSE IL2RG_MOUSE]] Common subunit for the receptors for a variety of interleukins. [[http://www.uniprot.org/uniprot/IL2RB_MOUSE IL2RB_MOUSE]] Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
+__TOC__
+</StructureSection>
 [[Category: Baker, D]]
-[[Category: Silva, D.-A]]
+[[Category: Garcia, K C]]
-[[Category: Jude, K.M]]
+[[Category: Jude, K M]]
-[[Category: Garcia, K.C]]
+[[Category: Silva, D A]]
 [[Category: Yu, S]]
+[[Category: Biosynthetic protein]]
+[[Category: Biosynthetic protein-protein binding complex]]
+[[Category: Cytokine mimetic]]
+[[Category: Cytokine receptor complex]]