6f9k: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6f9k is ~~ON HOLD until Paper Publication~~

==Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand==

~~Authors~~: ~~Stiel~~, A.C., ~~Shanmugaratnam~~, S., ~~Hocker~~, B.

== Structural highlights ==

<table><tr><td colspan='2'>[[6f9k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F9K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F9K FirstGlance]. <br>

~~Description~~: ~~Tryptophan Repressor TrpR from E~~.~~coli~~ with 5-~~methyl~~-~~L-tryptophan as ligand~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D0Q:5-methyl-L-tryptophan'>D0Q</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

~~[[Category: Unreleased Structures]]~~

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f9k OCA], [http://pdbe.org/6f9k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f9k RCSB], [http://www.ebi.ac.uk/pdbsum/6f9k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f9k ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

__TOC__

</StructureSection>

[[Category: Hocker, B]]

[[Category: Shanmugaratnam, S]]

[[Category: Stiel, A.C]]

[[Category: Stiel, A C]]

[[Category: Ligand binding]]

[[Category: Transcription]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6f9k is ON HOLD  until Paper Publication
+==Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand==
+<StructureSection load='6f9k' size='340' side='right' caption='[[6f9k]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
-Authors: Stiel, A.C., Shanmugaratnam, S., Hocker, B.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6f9k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F9K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F9K FirstGlance]. <br>
-Description: Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D0Q:5-methyl-L-tryptophan'>D0Q</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f9k OCA], [http://pdbe.org/6f9k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f9k RCSB], [http://www.ebi.ac.uk/pdbsum/6f9k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f9k ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
+__TOC__
+</StructureSection>
 [[Category: Hocker, B]]
 [[Category: Shanmugaratnam, S]]
-[[Category: Stiel, A.C]]
+[[Category: Stiel, A C]]
+[[Category: Ligand binding]]
+[[Category: Transcription]]