6fir: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 6fir is ON HOLD~~

==Human cytosolic 5'-nucleotidase II soaked with 5mM3-Phenyl-N-(9H-purin-6-yl)benzamide==

~~Authors: Aghajari, N., Preeti, P.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[6fir]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FIR OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FIR FirstGlance].

~~Description:~~ Human cytosolic 5'-nucleotidase II soaked with 5mM3-Phenyl-N-(9H-purin-6-yl)benzamide

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fir OCA], [http://pdbe.org/6fir PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fir RCSB], [http://www.ebi.ac.uk/pdbsum/6fir PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fir ProSAT]</td></tr>

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/5NTC_HUMAN 5NTC_HUMAN]] Autosomal recessive spastic paraplegia type 45. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:24482476</ref>

== Function ==

[[http://www.uniprot.org/uniprot/5NTC_HUMAN 5NTC_HUMAN]] May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.

== References ==

__TOC__

</StructureSection>

[[Category: 5'-nucleotidase]]

[[Category: Aghajari, N]]

[[Category: Preeti, P]]

[[Category: ~~Aghajari, N~~]]

[[Category: Hydrolase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6fir is ON HOLD
+==Human cytosolic 5'-nucleotidase II soaked with 5mM3-Phenyl-N-(9H-purin-6-yl)benzamide==
+<StructureSection load='6fir' size='340' side='right' caption='[[6fir]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-Authors: Aghajari, N., Preeti, P.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6fir]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FIR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FIR FirstGlance]. <br>
-Description: Human cytosolic 5'-nucleotidase II soaked with 5mM3-Phenyl-N-(9H-purin-6-yl)benzamide
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4h4b|4h4b]], [[5cqz|5cqz]], [[5cr7|5cr7]], [[2j2c|2j2c]]</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fir OCA], [http://pdbe.org/6fir PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fir RCSB], [http://www.ebi.ac.uk/pdbsum/6fir PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fir ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/5NTC_HUMAN 5NTC_HUMAN]] Autosomal recessive spastic paraplegia type 45. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:24482476</ref>
+== Function ==
+[[http://www.uniprot.org/uniprot/5NTC_HUMAN 5NTC_HUMAN]] May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: 5'-nucleotidase]]
+[[Category: Aghajari, N]]
 [[Category: Preeti, P]]
-[[Category: Aghajari, N]]
+[[Category: Hydrolase]]