6hp9: Difference between revisions
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==Structure of the kinase domain of human DDR1 in complex with a 2-Amino-2,3-Dihydro-1H-Indene-5-Carboxamide-based inhibitor== | |||
<StructureSection load='6hp9' size='340' side='right' caption='[[6hp9]], [[Resolution|resolution]] 1.96Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6hp9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HP9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HP9 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GKB:(2~{R})-~{N}-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-2-(pyrimidin-5-ylamino)-2,3-dihydro-1~{H}-indene-5-carboxamide'>GKB</scene></td></tr> | |||
[[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | ||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hp9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hp9 OCA], [http://pdbe.org/6hp9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hp9 RCSB], [http://www.ebi.ac.uk/pdbsum/6hp9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hp9 ProSAT]</span></td></tr> | ||
[[ | </table> | ||
[[ | __TOC__ | ||
[[ | </StructureSection> | ||
[[ | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: | [[Category: Arrowsmith, C H]] | ||
[[Category: | |||
[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
[[Category: Bullock, A | [[Category: Bullock, A N]] | ||
[[Category: Burgess-Brown, N A]] | |||
[[Category: Delft, F von]] | |||
[[Category: Edwards, A M]] | |||
[[Category: Fox, A E]] | |||
[[Category: Kupinska, K]] | [[Category: Kupinska, K]] | ||
[[Category: Pinkas, D M]] | |||
[[Category: Structural genomic]] | |||
[[Category: Ddr1]] | |||
[[Category: Sgc]] | |||
[[Category: Transferase]] | |||
Revision as of 08:27, 30 January 2019
Structure of the kinase domain of human DDR1 in complex with a 2-Amino-2,3-Dihydro-1H-Indene-5-Carboxamide-based inhibitor
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