6i1d: Difference between revisions
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==Structure of the Ysh1-Mpe1 nuclease complex from S.cerevisiae== | |||
<StructureSection load='6i1d' size='340' side='right' caption='[[6i1d]], [[Resolution|resolution]] 2.28Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6i1d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I1D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I1D FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i1d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i1d OCA], [http://pdbe.org/6i1d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i1d RCSB], [http://www.ebi.ac.uk/pdbsum/6i1d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i1d ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/YSH1_YEAST YSH1_YEAST]] Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Has endonuclease activity.<ref>PMID:15037765</ref> [[http://www.uniprot.org/uniprot/MPE1_YEAST MPE1_YEAST]] Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Boreikaite, V]] | |||
[[Category: Casanal, A]] | |||
[[Category: Degliesposti, G]] | |||
[[Category: Girbig, M]] | |||
[[Category: Hill, C H]] | |||
[[Category: Kubik, P]] | |||
[[Category: Kumar, A]] | |||
[[Category: Loeffelholz, O von]] | |||
[[Category: Mariani, A]] | |||
[[Category: Maslen, S]] | |||
[[Category: Passmore, L A]] | |||
[[Category: Skehel, M]] | |||
[[Category: 3' end]] | |||
[[Category: Cleavage]] | |||
[[Category: Cpf]] | |||
[[Category: Endonuclease]] | |||
[[Category: Gene regulation]] | |||
[[Category: Metallo-beta-lactamase]] | |||
[[Category: Mrna]] | |||
[[Category: Nuclease]] | |||
[[Category: Polya]] | |||
[[Category: Polyadenylation]] | |||
[[Category: Pre-mrna]] | |||
