6m7k: Difference between revisions
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==Structure of mouse RECON (AKR1C13) in complex with cyclic AMP-AMP-GMP (cAAG)== | |||
<StructureSection load='6m7k' size='340' side='right' caption='[[6m7k]], [[Resolution|resolution]] 1.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6m7k]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M7K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6M7K FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6m7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m7k OCA], [http://pdbe.org/6m7k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6m7k RCSB], [http://www.ebi.ac.uk/pdbsum/6m7k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6m7k ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/AK1CD_MOUSE AK1CD_MOUSE]] Catalyzes the dehydrogenation of 17-beta-hydroxysteroids. May also exhibit significant activity with a variety of cyclic and alicyclic alcohols. Uses both NAD and NADP, but the activity is much greater with NAD than with NADP (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Eaglesham, J B]] | |||
[[Category: King, D S]] | |||
[[Category: Kranzusch, P J]] | |||
[[Category: Lee, A S.Y]] | |||
[[Category: Mann, C C.de Oliveira]] | |||
[[Category: Mekalanos, J J]] | |||
[[Category: Morehouse, B R]] | |||
[[Category: Nieminen, E A]] | |||
[[Category: Whiteley, A T]] | |||
[[Category: Akr1c13]] | |||
[[Category: Cyclic amp-amp-gmp]] | |||
[[Category: Innate immunity]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Recon]] | |||