5zym: Difference between revisions
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==Crystal structure of CERT START domain in complex with compound E25B== | |||
<StructureSection load='5zym' size='340' side='right' caption='[[5zym]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5zym]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZYM FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9M6:2-[4-[4-cyclopentyl-3-[(1~{R},2~{S})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol'>9M6</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5zyg|5zyg]], [[5zyh|5zyh]], [[5zyi|5zyi]], [[5zyj|5zyj]], [[5zyk|5zyk]], [[5zyl|5zyl]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zym OCA], [http://pdbe.org/5zym PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zym RCSB], [http://www.ebi.ac.uk/pdbsum/5zym PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zym ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/C43BP_HUMAN C43BP_HUMAN]] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Egawa, D]] | |||
[[Category: Hanada, K]] | |||
[[Category: Hanzawa, H]] | |||
[[Category: Kawasaki, S]] | |||
[[Category: Kobayashi, S]] | [[Category: Kobayashi, S]] | ||
[[Category: Kumagai, K]] | [[Category: Kumagai, K]] | ||
[[Category: Nakao, N]] | [[Category: Nakao, N]] | ||
[[Category: Sakai, S]] | [[Category: Sakai, S]] | ||
[[Category: | [[Category: Suzuki, M]] | ||
[[Category: Ueno, M]] | [[Category: Ueno, M]] | ||
[[Category: Cert]] | |||
[[Category: Complex]] | |||
[[Category: Lipid transport]] | |||
[[Category: Ph]] | |||
[[Category: Start]] | |||