Sandbox Reserved 1482: Difference between revisions

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The main medication to treat hemophilia A is concentrated factor VIII protein, called “clotting factor”. Getting this “clotting factor” is therefore a major concern for hemophilia-affected people <ref name="Srivastava" />.
The main medication to treat hemophilia A is concentrated factor VIII protein, called “clotting factor”. Getting this “clotting factor” is therefore a major concern for hemophilia-affected people <ref name="Srivastava" />.


Nowadays, recombinant coagulation factor VIII products, which are developed in a lab through the use of DNA technology <ref name="El" /><ref name="toole" />. For instance, Toole and colleagues have created a biologically fully active factor with improved heterologous expression efficiency by deleting the B-domain from the native human factor VIII <ref name="toole" />.  
Nowadays, recombinant coagulation factor VIII products are developed in labs through the use of DNA technology <ref name="El" /><ref name="toole" />. For instance, Toole and colleagues have created a biologically fully active factor with improved heterologous expression efficiency by deleting the B-domain from the native human factor VIII <ref name="toole" />.