5zhm: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5zhm ~~is ON HOLD~~ ~~until Paper Publication~~

==Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor==

~~Authors~~: ~~Zhong, W~~.~~, Pasunooti, K~~.K., ~~Balamkundu~~, S., ~~Wong~~, Y.W., ~~Nah~~, Q., ~~Liu, C~~.F.~~, Lescar, J~~., ~~Dedon, P~~.C.

== Structural highlights ==

<table><tr><td colspan='2'>[[5zhm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZHM OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZHM FirstGlance].

~~Description~~: ~~Crystal structure of TrmD from Pseudomonas aeruginosa~~ in ~~complex with active-site inhibitor~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=9D3:N-({4-[(diethylamino)methyl]phenyl}methyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-5-carboxamide'>9D3</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zhm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zhm OCA], [http://pdbe.org/5zhm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zhm RCSB], [http://www.ebi.ac.uk/pdbsum/5zhm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zhm ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/TRMD_PSEAB TRMD_PSEAB]] Specifically methylates guanosine-37 in various tRNAs.

__TOC__

</StructureSection>

[[Category: Balamkundu, S]]

[[Category: Dedon, P C]]

[[Category: Lescar, J]]

~~[[Category: Balamkundu, S]]~~

[[Category: Liu, C F]]

~~[[Category: Pasunooti, K.K]]~~

~~[[Category: Wong, Y.W]]~~

[[Category: Liu, C.F]]

[[Category: Nah, Q]]

[[Category: ~~Dedon~~, ~~P.C~~]]

[[Category: Pasunooti, K K]]

[[Category: Wong, Y W]]

[[Category: Zhong, W]]

[[Category: Transferase]]

[[Category: Trna methyltransferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5zhm is ON HOLD  until Paper Publication
+==Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor==
+<StructureSection load='5zhm' size='340' side='right'  caption='[[5zhm]], [[Resolution|resolution]] 2.76&Aring;' scene=''>
-Authors: Zhong, W., Pasunooti, K.K., Balamkundu, S., Wong, Y.W., Nah, Q., Liu, C.F., Lescar, J., Dedon, P.C.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5zhm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZHM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZHM FirstGlance]. <br>
-Description: Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9D3:N-({4-[(diethylamino)methyl]phenyl}methyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-5-carboxamide'>9D3</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zhm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zhm OCA], [http://pdbe.org/5zhm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zhm RCSB], [http://www.ebi.ac.uk/pdbsum/5zhm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zhm ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/TRMD_PSEAB TRMD_PSEAB]] Specifically methylates guanosine-37 in various tRNAs.
+__TOC__
+</StructureSection>
+[[Category: Balamkundu, S]]
+[[Category: Dedon, P C]]
 [[Category: Lescar, J]]
-[[Category: Balamkundu, S]]
+[[Category: Liu, C F]]
-[[Category: Pasunooti, K.K]]
-[[Category: Wong, Y.W]]
-[[Category: Liu, C.F]]
 [[Category: Nah, Q]]
-[[Category: Dedon, P.C]]
+[[Category: Pasunooti, K K]]
+[[Category: Wong, Y W]]
 [[Category: Zhong, W]]
+[[Category: Transferase]]
+[[Category: Trna methyltransferase]]