6i5c: Difference between revisions
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==Long wavelength native-SAD phasing of Tubulin-Stathmin-TTL complex== | |||
<StructureSection load='6i5c' size='340' side='right'caption='[[6i5c]], [[Resolution|resolution]] 2.95Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6i5c]] is a 6 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4wbn 4wbn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I5C FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
[[ | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wbn|4wbn]]</td></tr> | ||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i5c OCA], [http://pdbe.org/6i5c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i5c RCSB], [http://www.ebi.ac.uk/pdbsum/6i5c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i5c ProSAT]</span></td></tr> | ||
[[ | </table> | ||
[[ | == Function == | ||
[[ | [[http://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref> [[http://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/TBB2B_BOVIN TBB2B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). | ||
[[ | == References == | ||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Basquin, J]] | [[Category: Basquin, J]] | ||
[[Category: Basu, S]] | [[Category: Basu, S]] | ||
[[Category: Diederichs, K]] | |||
[[Category: Huang, C Y]] | |||
[[Category: Kawano, Y]] | [[Category: Kawano, Y]] | ||
[[Category: | [[Category: Leonarski, F]] | ||
[[Category: Matsugaki, N]] | |||
[[Category: Olieric, N]] | |||
[[Category: Olieric, V]] | |||
[[Category: Takashi, T]] | |||
[[Category: Vera, L]] | [[Category: Vera, L]] | ||
[[Category: Wang, M]] | |||
[[Category: Wojdyla, J A]] | |||
[[Category: Yamada, Y]] | [[Category: Yamada, Y]] | ||
[[Category: | [[Category: Yamamoto, M]] | ||
[[Category: | [[Category: Long-wavelength native-sad phasing]] | ||
[[Category: | [[Category: Native-sad]] | ||
[[Category: S-sad]] | |||
[[Category: Structural protein]] | |||
[[Category: T2r-ttl]] | |||
[[Category: Tubulin complex]] | |||