6cqc: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6cqc is ~~ON HOLD until Paper Publication~~

==RNase P protein from Thermotoga maritima in complex with 1-(4-Fluorophenyl)-2-thiourea==

~~Authors~~: ~~Torres~~-~~Larios~~, A., ~~Madrigal-Carrillo~~, E.A.

== Structural highlights ==

<table><tr><td colspan='2'>[[6cqc]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CQC OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CQC FirstGlance].

~~Description~~: ~~RNase P~~ protein ~~from Thermotoga maritima~~ in ~~complex with 1~~-(~~4-Fluorophenyl~~)~~-2-thiourea~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=8P4:1-(4-FLUOROPHENYL)THIOUREA'>8P4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Ribonuclease_P Ribonuclease P], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.5 3.1.26.5] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cqc OCA], [http://pdbe.org/6cqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cqc RCSB], [http://www.ebi.ac.uk/pdbsum/6cqc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cqc ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/RNPA_THEMA RNPA_THEMA]] RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity).

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Ribonuclease P]]

[[Category: Madrigal-Carrillo, E A]]

[[Category: Torres-Larios, A]]

[[Category: ~~Madrigal-Carrillo, E.A~~]]

[[Category: Rna binding protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6cqc is ON HOLD  until Paper Publication
+==RNase P protein from Thermotoga maritima in complex with 1-(4-Fluorophenyl)-2-thiourea==
+<StructureSection load='6cqc' size='340' side='right'caption='[[6cqc]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
-Authors: Torres-Larios, A., Madrigal-Carrillo, E.A.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6cqc]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CQC FirstGlance]. <br>
-Description: RNase P protein from Thermotoga maritima in complex with 1-(4-Fluorophenyl)-2-thiourea
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8P4:1-(4-FLUOROPHENYL)THIOUREA'>8P4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_P Ribonuclease P], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.5 3.1.26.5] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cqc OCA], [http://pdbe.org/6cqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cqc RCSB], [http://www.ebi.ac.uk/pdbsum/6cqc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cqc ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/RNPA_THEMA RNPA_THEMA]] RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Ribonuclease P]]
+[[Category: Madrigal-Carrillo, E A]]
 [[Category: Torres-Larios, A]]
-[[Category: Madrigal-Carrillo, E.A]]
+[[Category: Rna binding protein]]