6ixf: Difference between revisions
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==Crystal structure of SeMet apo SH3BP5 (P41)== | |||
<StructureSection load='6ixf' size='340' side='right'caption='[[6ixf]], [[Resolution|resolution]] 3.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ixf]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IXF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IXF FirstGlance]. <br> | |||
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ixf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ixf OCA], [http://pdbe.org/6ixf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ixf RCSB], [http://www.ebi.ac.uk/pdbsum/6ixf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ixf ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/3BP5_HUMAN 3BP5_HUMAN]] Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.<ref>PMID:10339589</ref> <ref>PMID:9571151</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Fukai, S]] | |||
[[Category: Goto-Ito, S]] | |||
[[Category: Sato, Y]] | |||
[[Category: Yamagata, A]] | |||
[[Category: Gef]] | |||
[[Category: Rab11]] | |||
[[Category: Sh3bp5]] | |||
[[Category: Signaling protein]] | |||
Revision as of 07:59, 20 March 2019
Crystal structure of SeMet apo SH3BP5 (P41)
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