4crd: Difference between revisions
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==Creating novel F1 inhibitors through fragment based lead generation and structure aided drug design== | ==Creating novel F1 inhibitors through fragment based lead generation and structure aided drug design== | ||
<StructureSection load='4crd' size='340' side='right' caption='[[4crd]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='4crd' size='340' side='right'caption='[[4crd]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4crd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CRD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CRD FirstGlance]. <br> | <table><tr><td colspan='2'>[[4crd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CRD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CRD FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OTJ:METHYL+N-[4-[5-CHLORO-2-[[3-[5-CHLORO-2-(TETRAZOL-1-YL)PHENYL]PROPANOYLAMINO]METHYL]-1H-IMIDAZOL-4-YL]PHENYL]CARBAMATE'>OTJ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OTJ:METHYL+N-[4-[5-CHLORO-2-[[3-[5-CHLORO-2-(TETRAZOL-1-YL)PHENYL]PROPANOYLAMINO]METHYL]-1H-IMIDAZOL-4-YL]PHENYL]CARBAMATE'>OTJ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cr5|4cr5]], [[4cr9|4cr9]], [[4cra|4cra]], [[4crb|4crb]], [[4crc|4crc]], [[4cre|4cre]], [[4crf|4crf]], [[4crg|4crg]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cr5|4cr5]], [[4cr9|4cr9]], [[4cra|4cra]], [[4crb|4crb]], [[4crc|4crc]], [[4cre|4cre]], [[4crf|4crf]], [[4crg|4crg]]</td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Coagulation factor XIa]] | [[Category: Coagulation factor XIa]] | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Akkaya, S]] | [[Category: Akkaya, S]] | ||
[[Category: Beisel, H G]] | [[Category: Beisel, H G]] | ||
