4cmt: Difference between revisions

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==Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor 3-((1R)-1-(5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)ethoxy)- 5-(3-(methylsulfonyl)phenyl)pyridin-2-amine==
==Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor 3-((1R)-1-(5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)ethoxy)- 5-(3-(methylsulfonyl)phenyl)pyridin-2-amine==
<StructureSection load='4cmt' size='340' side='right' caption='[[4cmt]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
<StructureSection load='4cmt' size='340' side='right'caption='[[4cmt]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4cmt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CMT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CMT FirstGlance]. <br>
<table><tr><td colspan='2'>[[4cmt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CMT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CMT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GWH:3-{(1R)-1-[2-(1,3-DIHYDRO-2H-1,2,3-TRIAZOL-2-YL)-5-FLUOROPHENYL]ETHOXY}-5-[3-(METHYLSULFONYL)PHENYL]PYRIDIN-2-AMINE'>GWH</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GWH:3-{(1R)-1-[2-(1,3-DIHYDRO-2H-1,2,3-TRIAZOL-2-YL)-5-FLUOROPHENYL]ETHOXY}-5-[3-(METHYLSULFONYL)PHENYL]PYRIDIN-2-AMINE'>GWH</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cli|4cli]], [[4clj|4clj]], [[4cmo|4cmo]], [[4cmu|4cmu]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cli|4cli]], [[4clj|4clj]], [[4cmo|4cmo]], [[4cmu|4cmu]]</td></tr>
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</div>
</div>
<div class="pdbe-citations 4cmt" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4cmt" style="background-color:#fffaf0;"></div>
==See Also==
*[[Tyrosine kinase|Tyrosine kinase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Brooun, A]]
[[Category: Brooun, A]]