5yd6: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5yd6 is ~~ON HOLD until Paper Publication~~

==Crystal structure of PG-bound Nurr1-LBD==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5yd6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YD6 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YD6 FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=8SU:(~{Z})-7-[(1~{R},5~{S})-2-oxidanylidene-5-[(~{E},3~{S})-3-oxidanyloct-1-enyl]cyclopent-3-en-1-yl]hept-5-enoic+acid'>8SU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5y41|5y41]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yd6 OCA], [http://pdbe.org/5yd6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yd6 RCSB], [http://www.ebi.ac.uk/pdbsum/5yd6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yd6 ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/NR4A2_HUMAN NR4A2_HUMAN]] Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity).

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Sreekanth, R]]

[[Category: Yoon, H S]]

[[Category: Lbd]]

[[Category: Michael addition]]

[[Category: Nurr1]]

[[Category: Prostaglandin]]

[[Category: Transcription]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5yd6 is ON HOLD  until Paper Publication
+==Crystal structure of PG-bound Nurr1-LBD==
+<StructureSection load='5yd6' size='340' side='right'caption='[[5yd6]], [[Resolution|resolution]] 2.34&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5yd6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YD6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YD6 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8SU:(~{Z})-7-[(1~{R},5~{S})-2-oxidanylidene-5-[(~{E},3~{S})-3-oxidanyloct-1-enyl]cyclopent-3-en-1-yl]hept-5-enoic+acid'>8SU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5y41|5y41]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yd6 OCA], [http://pdbe.org/5yd6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yd6 RCSB], [http://www.ebi.ac.uk/pdbsum/5yd6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yd6 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/NR4A2_HUMAN NR4A2_HUMAN]] Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Sreekanth, R]]
+[[Category: Yoon, H S]]
+[[Category: Lbd]]
+[[Category: Michael addition]]
+[[Category: Nurr1]]
+[[Category: Prostaglandin]]
+[[Category: Transcription]]