6dii: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6dii is ~~ON HOLD until Paper Publication~~

==Structure of Arabidopsis Fatty Acid Amide Hydrolase in Complex with methyl linolenyl fluorophosphonate==

~~Authors~~: ~~Aziz~~, M., ~~Wang~~, X., ~~Tripathi~~, A., ~~Bankaitis~~, V., ~~Chapman~~, K.D.

== Structural highlights ==

<table><tr><td colspan='2'>[[6dii]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DII OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DII FirstGlance].

~~Description~~: ~~Structure of Arabidopsis~~ Fatty ~~Acid Amide Hydrolase in Complex with methyl linolenyl fluorophosphonate~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=GJY:methyl-9Z,12Z,15Z-octadecatrienylphosphonofluoridate'>GJY</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[6dhv|6dhv]]</td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Fatty_acid_amide_hydrolase Fatty acid amide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.99 3.5.1.99] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dii OCA], [http://pdbe.org/6dii PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dii RCSB], [http://www.ebi.ac.uk/pdbsum/6dii PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dii ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/FAAH_ARATH FAAH_ARATH]] Degrades bioactive fatty acid amides to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Converts N-actylethanolamine (NAE) to ethanolamine. Can also use oleamide or 2-arachidonylglycerol as substrates, but not indole-3-acetamide, 1-naphtalene-acetamide, nicotinic acid amide or L-asparagine. Might be involved in abscisic acid signaling and plant defense through distinctly different mechanisms not involving the catalytic activity.<ref>PMID:12824167</ref> <ref>PMID:16880402</ref> <ref>PMID:18643971</ref> <ref>PMID:19801664</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Fatty acid amide hydrolase]]

[[Category: Large Structures]]

[[Category: Aziz, M]]

[[Category: Bankaitis, V]]

[[Category: Chapman, K D]]

[[Category: Tripathi, A]]

~~[[Category: Chapman, K.D]]~~

[[Category: Wang, X]]

[[Category: ~~Aziz, M~~]]

[[Category: Faah]]

[[Category: Hydrolase]]

[[Category: Nae signaling]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6dii is ON HOLD  until Paper Publication
+==Structure of Arabidopsis Fatty Acid Amide Hydrolase in Complex with methyl linolenyl fluorophosphonate==
+<StructureSection load='6dii' size='340' side='right'caption='[[6dii]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
-Authors: Aziz, M., Wang, X., Tripathi, A., Bankaitis, V., Chapman, K.D.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6dii]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DII OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DII FirstGlance]. <br>
-Description: Structure of Arabidopsis Fatty Acid Amide Hydrolase in Complex with methyl linolenyl fluorophosphonate
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GJY:methyl-9Z,12Z,15Z-octadecatrienylphosphonofluoridate'>GJY</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6dhv|6dhv]]</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fatty_acid_amide_hydrolase Fatty acid amide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.99 3.5.1.99] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dii OCA], [http://pdbe.org/6dii PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dii RCSB], [http://www.ebi.ac.uk/pdbsum/6dii PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dii ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/FAAH_ARATH FAAH_ARATH]] Degrades bioactive fatty acid amides to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Converts N-actylethanolamine (NAE) to ethanolamine. Can also use oleamide or 2-arachidonylglycerol as substrates, but not indole-3-acetamide, 1-naphtalene-acetamide, nicotinic acid amide or L-asparagine. Might be involved in abscisic acid signaling and plant defense through distinctly different mechanisms not involving the catalytic activity.<ref>PMID:12824167</ref> <ref>PMID:16880402</ref> <ref>PMID:18643971</ref> <ref>PMID:19801664</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Fatty acid amide hydrolase]]
+[[Category: Large Structures]]
+[[Category: Aziz, M]]
 [[Category: Bankaitis, V]]
+[[Category: Chapman, K D]]
 [[Category: Tripathi, A]]
-[[Category: Chapman, K.D]]
 [[Category: Wang, X]]
-[[Category: Aziz, M]]
+[[Category: Faah]]
+[[Category: Hydrolase]]
+[[Category: Nae signaling]]