6e53: Difference between revisions

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'''Unreleased structure'''


The entry 6e53 is ON HOLD  until Paper Publication
==Structure of TERT in complex with a novel telomerase inhibitor==
 
<StructureSection load='6e53' size='340' side='right'caption='[[6e53]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
Authors: Hernandez-Sanchez, W., Huang, W., Plucinsky, B., Garcia-Vazquez, N., Berdis, A.J., Skordalakes, E., Taylor, D.J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6e53]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E53 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E53 FirstGlance]. <br>
Description: Structure of TERT in complex with a novel telomerase inhibitor
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HUV:methyl+1-{2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-D-erythro-pentofuranosyl}-1H-indole-5-carboxylate'>HUV</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e53 OCA], [http://pdbe.org/6e53 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e53 RCSB], [http://www.ebi.ac.uk/pdbsum/6e53 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e53 ProSAT]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: RNA-directed DNA polymerase]]
[[Category: Berdis, A J]]
[[Category: Garcia-Vazquez, N]]
[[Category: Hernandez-Sanchez, W]]
[[Category: Huang, W]]
[[Category: Plucinsky, B]]
[[Category: Plucinsky, B]]
[[Category: Huang, W]]
[[Category: Garcia-Vazquez, N]]
[[Category: Berdis, A.J]]
[[Category: Skordalakes, E]]
[[Category: Skordalakes, E]]
[[Category: Hernandez-Sanchez, W]]
[[Category: Taylor, D J]]
[[Category: Taylor, D.J]]
[[Category: Catalytic subunit]]
[[Category: Telomerase]]
[[Category: Telomerase inhibitor]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 06:33, 27 March 2019

Structure of TERT in complex with a novel telomerase inhibitor

6e53, resolution 2.80Å

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