6jo3: Difference between revisions

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~~'''Unreleased structure'''~~

~~The~~ entry ~~6jo3~~ is ~~ON HOLD~~

==Crystal structure of (S)-3-O-geranylgeranylgryceryl phosphate synthase from Thermoplasma acidophilum in complex with substrate sn-glycerol-1-phosphate==

~~Authors~~: ~~Nemoto~~, N., ~~Miyazono~~, K., ~~Tanokura~~, M., ~~Yamagishi~~, A.

== Structural highlights ==

<table><tr><td colspan='2'>[[6jo3]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5b69 5b69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JO3 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JO3 FirstGlance].

~~Description~~: ~~Crystal structure~~ of (S)-3-O-~~geranylgeranylgryceryl~~ phosphate ~~synthase from Thermoplasma acidophilum~~ in ~~complex with substrate~~ sn-glycerol-1-phosphate

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=1GP:SN-GLYCEROL-1-PHOSPHATE'>1GP</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4mm1|4mm1]], [[2f6x|2f6x]]</td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Phosphoglycerol_geranylgeranyltransferase Phosphoglycerol geranylgeranyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.41 2.5.1.41] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jo3 OCA], [http://pdbe.org/6jo3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jo3 RCSB], [http://www.ebi.ac.uk/pdbsum/6jo3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jo3 ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/GGGPS_THEAC GGGPS_THEAC]] Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. Cannot use sn-glycerol-3-phosphate (G3P) as substrate.<ref>PMID:12801917</ref> <ref>PMID:24684232</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Phosphoglycerol geranylgeranyltransferase]]

[[Category: Miyazono, K]]

[[Category: Nemoto, N]]

[[Category: Tanokura, M]]

[[Category: Yamagishi, A]]

[[Category: ~~Tanokura, M~~]]

[[Category: Archaea]]

[[Category: ~~Miyazono, K~~]]

[[Category: Ether lipid]]

[[Category: Structural genomic]]

[[Category: Thermoplasma]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6jo3 is ON HOLD
+==Crystal structure of (S)-3-O-geranylgeranylgryceryl phosphate synthase from Thermoplasma acidophilum in complex with substrate sn-glycerol-1-phosphate==
+<StructureSection load='6jo3' size='340' side='right'caption='[[6jo3]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
-Authors: Nemoto, N., Miyazono, K., Tanokura, M., Yamagishi, A.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6jo3]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5b69 5b69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JO3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JO3 FirstGlance]. <br>
-Description: Crystal structure of (S)-3-O-geranylgeranylgryceryl phosphate synthase from Thermoplasma acidophilum in complex with substrate sn-glycerol-1-phosphate
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1GP:SN-GLYCEROL-1-PHOSPHATE'>1GP</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mm1|4mm1]], [[2f6x|2f6x]]</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoglycerol_geranylgeranyltransferase Phosphoglycerol geranylgeranyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.41 2.5.1.41] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jo3 OCA], [http://pdbe.org/6jo3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jo3 RCSB], [http://www.ebi.ac.uk/pdbsum/6jo3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jo3 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/GGGPS_THEAC GGGPS_THEAC]] Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. Cannot use sn-glycerol-3-phosphate (G3P) as substrate.<ref>PMID:12801917</ref> <ref>PMID:24684232</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Phosphoglycerol geranylgeranyltransferase]]
+[[Category: Miyazono, K]]
 [[Category: Nemoto, N]]
+[[Category: Tanokura, M]]
 [[Category: Yamagishi, A]]
-[[Category: Tanokura, M]]
+[[Category: Archaea]]
-[[Category: Miyazono, K]]
+[[Category: Ether lipid]]
+[[Category: Structural genomic]]
+[[Category: Thermoplasma]]
+[[Category: Transferase]]