6o62: Difference between revisions
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==Crystal structure of Sec4p, a Rab family GTPase from Candida albicans== | |||
<StructureSection load='6o62' size='340' side='right'caption='[[6o62]], [[Resolution|resolution]] 1.88Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6o62]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O62 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6O62 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6o62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o62 OCA], [http://pdbe.org/6o62 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6o62 RCSB], [http://www.ebi.ac.uk/pdbsum/6o62 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6o62 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/SEC4_CANAL SEC4_CANAL]] Involved in exocytosis. Maybe by regulating the binding and fusion of secretory vesicles with the cell surface. The GTP-bound form of SEC4 may interact with an effector, thereby stimulating its activity and leading to exocytotic fusion. SEC4 may be an upstream activator of the 19.5S SEC8/SEC15 particle. SEC4 probably interacts directly with SEC8; it could serve as the attachment site for the SEC8/SEC15 particle (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Structural genomic]] | |||
[[Category: Leo, R Di]] | |||
[[Category: Savchenko, A]] | [[Category: Savchenko, A]] | ||
[[Category: Skarina, T]] | [[Category: Skarina, T]] | ||
[[Category: | [[Category: Stogios, P J]] | ||
[[Category: | [[Category: Csgid]] | ||
[[Category: G-protein]] | |||
[[Category: Gdp]] | |||
[[Category: Gtpase]] | |||
[[Category: P-loop]] | |||
[[Category: Protein binding]] | |||
[[Category: Rab]] | |||
Revision as of 07:10, 3 April 2019
Crystal structure of Sec4p, a Rab family GTPase from Candida albicans
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