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==Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis==
==Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis==
<StructureSection load='4ofe' size='340' side='right' caption='[[4ofe]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='4ofe' size='340' side='right'caption='[[4ofe]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ofe]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OFE FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ofe]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OFE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3iho|3iho]], [[4ea5|4ea5]], [[4e9g|4e9g]], [[4e9e|4e9e]], [[4e9f|4e9f]], [[4ea4|4ea4]], [[4ofa|4ofa]], [[4ofh|4ofh]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3iho|3iho]], [[4ea5|4ea5]], [[4e9g|4e9g]], [[4e9e|4e9e]], [[4e9f|4e9f]], [[4ea4|4ea4]], [[4ofa|4ofa]], [[4ofh|4ofh]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MBD4, MED1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ofe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ofe OCA], [http://pdbe.org/4ofe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ofe RCSB], [http://www.ebi.ac.uk/pdbsum/4ofe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ofe ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ofe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ofe OCA], [http://pdbe.org/4ofe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ofe RCSB], [http://www.ebi.ac.uk/pdbsum/4ofe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ofe ProSAT]</span></td></tr>
</table>
</table>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Lee, S]]
[[Category: Lee, S]]
[[Category: Lin, Y L]]
[[Category: Lin, Y L]]

Revision as of 08:08, 10 April 2019

Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis

4ofe, resolution 2.15Å

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