Uncoupling Protein 2: Difference between revisions

The disorder which affects the pancreas is caused by the A3243G mutation which causes diabetes. Bilateral hearing impairment is a symptom carried by the carrier of mitochondrial diabetes. Some other symptoms that can be seen is a change in pigmentation of the retina. <ref>Maassen, J. A.; Leen; Hart; Essen, E. van; Heine, R. J.; Nijpels, G.; Tafrechi, R. S. J.; Raap, A. K.; Janssen, G. M. C.; Lemkes, H. H. P. J. Mitochondrial Diabetes. http://diabetes.diabetesjournals.org/content/53/suppl_1/S103 (accessed Apr 1, 2019).</ref> This mutation can be seen around the age of 38 years old, this disease is age dependent in the fact that over time there is a deterioration of glucose homeostasis. The pattern of inhertitance of this disorder depends on the mitochondria of the mother and can be passed down to both male and female offspring.