6qji: Difference between revisions
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==Crystal Structure of the third PDZ domain of PSD-95 protein: space group P3112== | |||
<StructureSection load='6qji' size='340' side='right'caption='[[6qji]], [[Resolution|resolution]] 1.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6qji]] is a 6 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5oib 5oib]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QJI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QJI FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5oib|5oib]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qji OCA], [http://pdbe.org/6qji PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qji RCSB], [http://www.ebi.ac.uk/pdbsum/6qji PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qji ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/DLG4_HUMAN DLG4_HUMAN]] Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Camara-Artigas, A]] | [[Category: Camara-Artigas, A]] | ||
[[Category: Pdz domain]] | |||
[[Category: Signaling protein]] | |||
Revision as of 05:44, 17 April 2019
Crystal Structure of the third PDZ domain of PSD-95 protein: space group P3112
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