6qjn: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 6qjn is ON HOLD until Paper Publication~~

==Crystal Structure of the third PDZ domain of PSD-95 protein D332G mutant: space group I4122==

~~Authors: Camara-Artigas, A.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[6qjn]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5oij 5oij]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QJN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QJN FirstGlance]. <br>

~~Description:~~ Crystal Structure of the third PDZ domain of PSD-95 protein D332G mutant: space group I4122

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qjn OCA], [http://pdbe.org/6qjn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qjn RCSB], [http://www.ebi.ac.uk/pdbsum/6qjn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qjn ProSAT]</span></td></tr>

[[Category: ~~Unreleased~~ Structures]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/DLG4_HUMAN DLG4_HUMAN]] Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Camara-Artigas, A]]

[[Category: Pdz domain]]

[[Category: Signaling protein]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6qjn is ON HOLD  until Paper Publication
+==Crystal Structure of the third PDZ domain of PSD-95 protein D332G mutant: space group I4122==
+<StructureSection load='6qjn' size='340' side='right'caption='[[6qjn]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-Authors: Camara-Artigas, A.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6qjn]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5oij 5oij]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QJN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QJN FirstGlance]. <br>
-Description: Crystal Structure of the third PDZ domain of PSD-95 protein D332G mutant: space group I4122
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qjn OCA], [http://pdbe.org/6qjn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qjn RCSB], [http://www.ebi.ac.uk/pdbsum/6qjn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qjn ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/DLG4_HUMAN DLG4_HUMAN]] Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Camara-Artigas, A]]
+[[Category: Pdz domain]]
+[[Category: Signaling protein]]