6g77: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6g77 is ~~ON HOLD until Paper Publication~~

==RSK4 N-terminal Kinase Domain in complex with AMP-PNP==

~~Authors~~: ~~Prischi~~, F., ~~Ali~~, M.M.

== Structural highlights ==

<table><tr><td colspan='2'>[[6g77]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G77 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G77 FirstGlance].

~~Description~~: ~~RSK4 N~~-~~terminal Kinase Domain~~ in ~~complex with AMP~~-~~PNP~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g77 OCA], [http://pdbe.org/6g77 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g77 RCSB], [http://www.ebi.ac.uk/pdbsum/6g77 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g77 ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/KS6A6_HUMAN KS6A6_HUMAN]] Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis.<ref>PMID:15042092</ref> <ref>PMID:15632195</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Non-specific serine/threonine protein kinase]]

[[Category: Ali, M M]]

[[Category: Prischi, F]]

[[Category: ~~Ali, M.M~~]]

[[Category: Agc kinase]]

[[Category: P90 ribosomal s6 kinase]]

[[Category: Rsk4]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6g77 is ON HOLD  until Paper Publication
+==RSK4 N-terminal Kinase Domain in complex with AMP-PNP==
+<StructureSection load='6g77' size='340' side='right'caption='[[6g77]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-Authors: Prischi, F., Ali, M.M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6g77]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G77 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G77 FirstGlance]. <br>
-Description: RSK4 N-terminal Kinase Domain in complex with AMP-PNP
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g77 OCA], [http://pdbe.org/6g77 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g77 RCSB], [http://www.ebi.ac.uk/pdbsum/6g77 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g77 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/KS6A6_HUMAN KS6A6_HUMAN]] Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis.<ref>PMID:15042092</ref> <ref>PMID:15632195</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Non-specific serine/threonine protein kinase]]
+[[Category: Ali, M M]]
 [[Category: Prischi, F]]
-[[Category: Ali, M.M]]
+[[Category: Agc kinase]]
+[[Category: P90 ribosomal s6 kinase]]
+[[Category: Rsk4]]
+[[Category: Transferase]]