4p8o: Difference between revisions
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==S. aureus gyrase bound to an aminobenzimidazole urea inhibitor== | ==S. aureus gyrase bound to an aminobenzimidazole urea inhibitor== | ||
<StructureSection load='4p8o' size='340' side='right' caption='[[4p8o]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='4p8o' size='340' side='right'caption='[[4p8o]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4p8o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P8O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P8O FirstGlance]. <br> | <table><tr><td colspan='2'>[[4p8o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staa4 Staa4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P8O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P8O FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=883:1-ETHYL-3-[5-(5-FLUOROPYRIDIN-3-YL)-7-(PYRIMIDIN-2-YL)-1H-BENZIMIDAZOL-2-YL]UREA'>883</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=883:1-ETHYL-3-[5-(5-FLUOROPYRIDIN-3-YL)-7-(PYRIMIDIN-2-YL)-1H-BENZIMIDAZOL-2-YL]UREA'>883</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gyrB, SAR0005 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=703339 STAA4])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p8o OCA], [http://pdbe.org/4p8o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p8o RCSB], [http://www.ebi.ac.uk/pdbsum/4p8o PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p8o OCA], [http://pdbe.org/4p8o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p8o RCSB], [http://www.ebi.ac.uk/pdbsum/4p8o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p8o ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Staa4]] | |||
[[Category: Jacobs, M D]] | [[Category: Jacobs, M D]] | ||
[[Category: Antibacterial]] | [[Category: Antibacterial]] | ||
