6qby: Difference between revisions
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==Crystal structure of VASH 2 in complex with SVBP== | |||
<StructureSection load='6qby' size='340' side='right'caption='[[6qby]], [[Resolution|resolution]] 2.09Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6qby]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QBY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QBY FirstGlance]. <br> | |||
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tubulinyl-Tyr_carboxypeptidase Tubulinyl-Tyr carboxypeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.17 3.4.17.17] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qby OCA], [http://pdbe.org/6qby PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qby RCSB], [http://www.ebi.ac.uk/pdbsum/6qby PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qby ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/SVBP_HUMAN SVBP_HUMAN]] Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin (PubMed:29146869). Also required to enhance the solubility and secretion of VASH1 and VASH2 (PubMed:20736312, PubMed:27879017).<ref>PMID:20736312</ref> <ref>PMID:27879017</ref> <ref>PMID:29146869</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Tubulinyl-Tyr carboxypeptidase]] | |||
[[Category: Choi, S R]] | |||
[[Category: Olieric, N]] | |||
[[Category: Olieric, V]] | |||
[[Category: Steinmetz, M O]] | |||
[[Category: Complex]] | |||
[[Category: Cysteine protease]] | |||
[[Category: Cytosolic protein]] | |||
[[Category: Tubulin carboxypeptidase]] | |||
Revision as of 07:11, 24 April 2019
Crystal structure of VASH 2 in complex with SVBP
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