5aep: Difference between revisions

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==Novel pyrrole carboxamide inhibitors of JAK2 as potential treatment of myeloproliferative disorders==
==Novel pyrrole carboxamide inhibitors of JAK2 as potential treatment of myeloproliferative disorders==
<StructureSection load='5aep' size='340' side='right' caption='[[5aep]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='5aep' size='340' side='right'caption='[[5aep]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5aep]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AEP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AEP FirstGlance]. <br>
<table><tr><td colspan='2'>[[5aep]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AEP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AEP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=QUP:1-(5-CHLORO-2-METHYLPHENYL)-4-(PYRROLO[2,1-F][1,2,4]TRIAZIN-4-YL)-1H-PYRROLE-2-CARBOXAMIDE'>QUP</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=QUP:1-(5-CHLORO-2-METHYLPHENYL)-4-(PYRROLO[2,1-F][1,2,4]TRIAZIN-4-YL)-1H-PYRROLE-2-CARBOXAMIDE'>QUP</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Amboldi, N]]
[[Category: Amboldi, N]]
Retrieved from "https://proteopedia.org/5aep"