6r65: Difference between revisions

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'''Unreleased structure'''


The entry 6r65 is ON HOLD
==Crystal Structure of human TMEM16K / Anoctamin 10 (Form 2)==
 
<StructureSection load='6r65' size='340' side='right'caption='[[6r65]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
Authors: Bushell, S.R., Pike, A.C.W., Chu, A., Tessitore, A., Rotty, B., Mukhopadhyay, S., Kupinska, K., Shrestha, L., Borkowska, O., Chalk, R., Burgess-Brown, N.A., Love, J., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6r65]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R65 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6R65 FirstGlance]. <br>
Description: Crystal Structure of human TMEM16K / Anoctamin 10 (Form 2)
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5oc9|5oc9]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6r65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r65 OCA], [http://pdbe.org/6r65 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6r65 RCSB], [http://www.ebi.ac.uk/pdbsum/6r65 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6r65 ProSAT]</span></td></tr>
</table>
== Disease ==
[[http://www.uniprot.org/uniprot/ANO10_HUMAN ANO10_HUMAN]] Adult-onset autosomal recessive cerebellar ataxia. The disease is caused by mutations affecting the gene represented in this entry.  
== Function ==
[[http://www.uniprot.org/uniprot/ANO10_HUMAN ANO10_HUMAN]] Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1.<ref>PMID:20056604</ref> <ref>PMID:22946059</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Borkowska, O]]
[[Category: Bountra, C]]
[[Category: Burgess-Brown, N A]]
[[Category: Bushell, S R]]
[[Category: Carpenter, E P]]
[[Category: Chalk, R]]
[[Category: Chu, A]]
[[Category: Edwards, A M]]
[[Category: Kupinska, K]]
[[Category: Love, J]]
[[Category: Mukhopadhyay, S]]
[[Category: Pike, A C.W]]
[[Category: Rotty, B]]
[[Category: Rotty, B]]
[[Category: Pike, A.C.W]]
[[Category: Structural genomic]]
[[Category: Arrowsmith, C.H]]
[[Category: Chalk, R]]
[[Category: Borkowska, O]]
[[Category: Shrestha, L]]
[[Category: Shrestha, L]]
[[Category: Love, J]]
[[Category: Burgess-Brown, N.A]]
[[Category: Chu, A]]
[[Category: Tessitore, A]]
[[Category: Tessitore, A]]
[[Category: Edwards, A.M]]
[[Category: Calcium activation]]
[[Category: Mukhopadhyay, S]]
[[Category: Lipid transport]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: Membrane protein]]
[[Category: Carpenter, E.P]]
[[Category: Sgc]]
[[Category: Bountra, C]]
[[Category: Transport protein]]
[[Category: Bushell, S.R]]
[[Category: Kupinska, K]]
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