4rn6: Difference between revisions

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==Structure of prethrombin-2 mutant s195a bound to the active site inhibitor argatroban==

== Structural highlights ==

<table><tr><td colspan='2'>[[4rn6]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4hfy 4hfy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RN6 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RN6 FirstGlance].

<table><tr><td colspan='2'>[[4rn6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4hfy 4hfy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RN6 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RN6 FirstGlance].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=15U:(2R,4R)-4-METHYL-1-(N~2~-{[(3S)-3-METHYL-1,2,3,4-TETRAHYDROQUINOLIN-8-YL]SULFONYL}-L-ARGINYL)PIPERIDINE-2-CARBOXYLIC+ACID'>15U</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[3sqh|3sqh]]</td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">F2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rn6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rn6 OCA], [http://pdbe.org/4rn6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rn6 RCSB], [http://www.ebi.ac.uk/pdbsum/4rn6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rn6 ProSAT]</td></tr>

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__TOC__

</StructureSection>

[[Category: Human]]

[[Category: Large Structures]]

[[Category: Thrombin]]

[[Category: Barranco-Medina, S]]

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@@ Line 1: / Line 1: @@
 ==Structure of prethrombin-2 mutant s195a bound to the active site inhibitor argatroban==
-<StructureSection load='4rn6' size='340' side='right' caption='[[4rn6]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
+<StructureSection load='4rn6' size='340' side='right'caption='[[4rn6]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4rn6]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4hfy 4hfy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RN6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RN6 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4rn6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4hfy 4hfy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RN6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RN6 FirstGlance]. <br>
 </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=15U:(2R,4R)-4-METHYL-1-(N~2~-{[(3S)-3-METHYL-1,2,3,4-TETRAHYDROQUINOLIN-8-YL]SULFONYL}-L-ARGINYL)PIPERIDINE-2-CARBOXYLIC+ACID'>15U</scene></td></tr>
 <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sqh|3sqh]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">F2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
 <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span></td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rn6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rn6 OCA], [http://pdbe.org/4rn6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rn6 RCSB], [http://www.ebi.ac.uk/pdbsum/4rn6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rn6 ProSAT]</span></td></tr>
@@ Line 29: / Line 30: @@
 __TOC__
 </StructureSection>
+[[Category: Human]]
+[[Category: Large Structures]]
 [[Category: Thrombin]]
 [[Category: Barranco-Medina, S]]