4rsp: Difference between revisions
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==X-ray structure of MERS-CoV nsp5 protease bound with a designed inhibitor== | ==X-ray structure of MERS-CoV nsp5 protease bound with a designed inhibitor== | ||
<StructureSection load='4rsp' size='340' side='right' caption='[[4rsp]], [[Resolution|resolution]] 1.62Å' scene=''> | <StructureSection load='4rsp' size='340' side='right'caption='[[4rsp]], [[Resolution|resolution]] 1.62Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4rsp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RSP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RSP FirstGlance]. <br> | <table><tr><td colspan='2'>[[4rsp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mers Mers]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RSP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RSP FirstGlance]. <br> | ||
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BOC:TERT-BUTYL+HYDROGEN+CARBONATE'>BOC</scene>, <scene name='pdbligand=CEV:ETHYL+(4R)-4-AMINO-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE'>CEV</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BOC:TERT-BUTYL+HYDROGEN+CARBONATE'>BOC</scene>, <scene name='pdbligand=CEV:ETHYL+(4R)-4-AMINO-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE'>CEV</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rsp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rsp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rsp RCSB], [http://www.ebi.ac.uk/pdbsum/4rsp PDBsum]</span></td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">orf1a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1335626 MERS])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rsp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rsp OCA], [http://pdbe.org/4rsp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rsp RCSB], [http://www.ebi.ac.uk/pdbsum/4rsp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rsp ProSAT]</span></td></tr> | |||
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4rsp" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[SARS Coronavirus Main Proteinase|SARS Coronavirus Main Proteinase]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Mers]] | |||
[[Category: Mesecar, A D]] | [[Category: Mesecar, A D]] | ||
[[Category: Tomar, S]] | [[Category: Tomar, S]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
